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Topical Melatonin for Hair Loss

An emerging scalp-focused ingredient in personalised hair-loss formulations

From          /100ml

£60

Apply 1ml once daily, 100ml bottle lasts approximately 3 months at this rate.

Topical melatonin formulation for hair loss

From          /100ml

£60

Formulated without propylene glycol. see why

What is Topical Melatonin?

Melatonin is a hormone naturally produced by the body that also has antioxidant properties.

Research has explored its potential effects on hair follicles, particularly in androgenetic alopecia, where oxidative stress and follicle ageing may contribute to progressive miniaturisation.

How does topical Melatonin work?

Potential mechanisms include:

Antioxidant activity

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Melatonin may help reduce oxidative stress around the hair follicle, which could support a healthier follicular environment.

Supporting the hair growth cycle

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Some research suggests melatonin may influence signalling pathways involved in the hair cycle, particularly the growth (anagen) phase.

Supporting follicle health

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By influencing the local scalp environment, melatonin may help support vulnerable follicles.

What strength is used?

A commonly used topical concentration is: Melatonin 0.1%
 

The formulation may be personalised depending on:
 

  • Individual treatment goals
     

  • Scalp sensitivity
     

  • Other active ingredients included

PERSONALISED FORMULATIONS

Combination formulations

Melatonin may be combined with:

  • Minoxidil 

  • Dutasteride

  • Finasteride

  • Other supportive ingredients

Who may consider topical Melatonin for hair loss?

  • Those with androgenetic (pattern) hair loss looking for an additional treatment option.

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  • Individuals wanting to use melatonin as an adjunct to established treatments, such as minoxidil or DHT-targeting treatments.

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  • Those interested in a personalised topical formulation following clinical assessment.

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  • People who may prefer to incorporate additional scalp-supporting ingredients into their hair-loss regimen.

Frequently Asked Questions

Does topical Melatonin have side effects?

Topical melatonin for hair loss is generally well tolerated, although some people may experience scalp irritation, redness, dryness or itching.

Will topical melatonin affect my natural melatonin levels?

Topical melatonin is intended to act locally on the scalp, and significant effects on your body's natural melatonin production are not expected. However, some absorption may occur, so individual suitability should be assessed before use.

How long does topical melatonin take to work?

​Hair growth is gradual, so consistent use over several months is generally needed before assessing whether it is providing a benefit.

IMPORTANT INFORMATION

This is an unlicensed medicine, prepared specifically for you following clinical assessment. It does not hold a UK marketing authorisation in this strength or formulation. Unlicensed medicines are used when no licensed product meets your individual clinical needs, in line with MHRA guidance on the supply of unlicensed medicines and GPhC standards for pharmacist prescribing

Is topical Melatonin suitable for you?

The first step is a clinical hair-loss assessment. Provide details about your hair loss, medical history, and scalp photographs so your case can be reviewed and an appropriate treatment approach considered.

​Prescription treatment is not guaranteed and will only be supplied where clinically appropriate.

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